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Translational research program

The translation of research discoveries into public benefit has become a focus for many research funding agencies and is particularly relevant for the Cancer Institute with a core aim of impacting upon population health.

Previous Outcomes

Here you can find details of the outcomes of past and currently funded grants in this program stream, including example application forms and guidelines.

2015

Translational Program Grants

The Cancer Institute NSW Translational Program Grants are focussed on supporting multi-disciplinary approaches to cancer research that will rapidly translate research discoveries into clinical programs or policy.

Applications

IDRecipientProject TitleAdministering InstitutionFunded
14/TPG/1-02 Professor Phyllis Butow A sustainable and supported clinical pathway for managing anxiety and depression in cancer patients: Developing and evaluating components and testing implementation strategies University of Sydney $3,643,992
14/TPG/1-05 Professor David Goldstein Chemotherapy-induced Peripheral Neuropathy: Assessment strategies, Treatments and Risk Factors University of New South Wales $3,044,654
14/TPG/1-13 Professor Glenn Marshall Experimental therapeutics for Myc-driven childhood cancer University of New South Wales $3,749,979
14/TPG/1-15 Professor Anna de Fazio INOVATe-Individualised Ovarian Cancer Treatment Through Integration of Genomic Pathology into Multidisciplinary Care University of Sydney $3,746,690
  $14,185,315

 

2013

Translational Cancer Research Centres (TRC)

The Translational Cancer Research program aims to encourage hubs of academic and clinical leaders with both substantial cancer treatment facilities and meritorious programs in relevant research disciplines to integrate into interdisciplinary and translational enterprises focussing on cancer control.

Applications

IDRecipientProject TitleAdministering InstitutionFunded
13/TRC/1-01 Professor Paul de Souza Centre for Oncology Education and Research Translation (CONCERT) University of New South Wales $6,499,980
13/TRC/1-02 Professor Stephen Ackland Hunter Cancer Research Alliance (HCRA) University of Newcastle $6,498,216
13/TRC/1-03 Associate Professor Alexander Engel Sydney Vital (formerly Northern Translational Cancer Research Centre (NTCRC)) University of Sydney $6,344,518
  $19,342,714

 

Big Data, Big Impact Grants (DATA)

The Big Data, Big Impact grants aim to bring together outstanding research teams to identify the potential within open access datasets. New and creative ideas are sought for research studies that facilitate new approaches to unlocking big data. The grants promote a novel way of conducting research using existing data and samples to accelerate scientific discoveries by connecting data to cancer outcomes.

Applications

IDRecipientProject TitleAdministering InstitutionFunded
13/DATA/1-01 A/Prof Daniel Catchpoole Generating Actionable Knowledge from Complex Genomic Data for Personalised Clinical Decisions University of New South Wales $60,000
13/DATA/1-02 Dr Jason Wong Exploring the "dark matter" of cancer genomes University of New South Wales $60,000
13/DATA/1-03 Prof Pablo Moscato The integration of bioinformatics, chemoinformatics, and toxicogenomics methods: a new approach for the identification of combination tailored therapies and novel drug targets in breast cancer University of Newcastle $58,000
13/DATA/1-06 Prof Rodney Scott Uncovering the link between obesity and cancer using random forests in an elastic cloud University of Newcastle $57,208
13/DATA/1-06 Dr Lina Pugliano The impact of hypoglycemic agent use on early breast cancer outcomes: an analysis of SEER-Medicare clinical data and the biological rationale St Vincent's and Mater Health Sydney $60,000
  $295,208

 

2011

Translational Program Grants

The Cancer Institute NSW Translational Program Grants are focussed on supporting multi-disciplinary approaches to cancer research that will rapidly translate research discoveries into clinical programs or policy.
IDRecipientProject TitleAdministering InstitutionFunded
11/TPG/3-02 Prof Derek Hart Enabling Diagnostic and Therapeutic Antibodies for Haematological and other Malignancies University of Sydney $3,466,923
11/TPG/3-06 Prof Nico van Zandwijk Translating Malignant Mesothelioma research into better outcomes for patients and their families Asbestos Diseases Research Institute $3,500.00
  $6,966,923

 

Translational Cancer Research Centres (TRC)

The Translational Cancer Research program aims to encourage hubs of academic and clinical leaders with both substantial cancer treatment facilities and meritorious programs in relevant research disciplines to integrate into interdisciplinary and translational enterprises focussing on cancer control.

Stage 1: Expressions of Interest

Stage 2: Full applications

IDRecipientProject TitleAdministering InstitutionFunded
11/TRC/1-01 Prof Robyn Ward South-Eastern Translational Cancer Research Centre University of New South Wales $6,500,000
11/TRC/1-02 Prof John Simes Sydney Catalyst: The Translational Cancer Research Centre of Central Sydney and Regional NSW University of Sydney $6,350,000
11/TRC/1-03 Prof Glenn Marshall A Translational Cancer Research Centre for Kids University of New South Wales $6,498,535
11/TRC/1-06 A/Prof Paul Harnett Sydney-West Translational Cancer Research Centre University of Sydney $6,500,000
  $25,848,535

 

Translational Cancer Research Units (TRU)

The Translational Cancer Research program aims to encourage hubs of academic and clinical leaders with both substantial cancer treatment facilities and meritorious programs in relevant research disciplines to integrate into interdisciplinary and translational enterprises focussing on cancer control.

IDRecipientProject TitleAdministering InstitutionFunded
11/TRU/1-08 Prof Stephen Ackland Hunter Translational Cancer Research Unit University of Newcastle $1,693,333*
11/TRU/1-09 Prof Paul de Souza South West Sydney Translational Cancer Research Unit Ingham Health Research Institute $1,793,333*
11/TRU/1-10 Prof Stephen Clarke Northern Translational Cancer Research Unit University of Sydney $1,792,844*
  $5,279,510

*Included within the Funding for each Translational Cancer Research Unit is $293,333 funded by NSW Health to establish a Fellowship Support Program.

 

2010

Cancer Epidemiology Linkage Innovation Grants

One year seed funding to allow researchers to establish proof of principle research opportunities for data linkage studies using CheReL to show how and where cancer outcomes and cancer services can be improved (max $50,000 in total)
IDRecipientProject TitleAdministering InstitutionFunded
10/EIN/2-01 Dr Efty Stavrou Validation of upper gastro-intestinal cancer surgical procedural and diagnostic codes in NSW University of New South Wales $50,000

 

Cancer Epidemiology Linkage Grants

Three year grants to provide research opportunities for data linkage studies using the centre for Health Record Linkage (CHeReL) to show how and where cancer outcomes and cancer services can be improved (max $100,000 p.a. + approved linkage costs paid directly to CHeReL).

IDRecipientProject TitleAdministering InstitutionFundedCHeReL LinkageTotal
10/EPI/2-05 A/Prof Dianne O'Connell Cancer Comorbidity, Treatment, Survival and End of Life Care for Aboriginal People in NSW Cancer Council NSW $272,265 $8,423 $280,688
10/EPI/2-06 Dr Claire Vajdic Health service utilisation and risk factors for cancer of unknown primary (CUP) University of New South Wales $296,558 $7,712 $304,270
10/EPI/2-07 Assoc Prof Jane Young Development and evaluation of composite clinical indicators of hospital performance for comparative assessment of the quality of surgical care for colorectal cancer University of Sydney $297,442 $25,510 $322,952
  $907,910

 

Innovation Grants

One year grants to allow researchers to establish data, proof-of-principal or an important research concept to promote innovation and expertise in NSW cancer research.

IDRecipientProject TitleAdministering InstitutionFunded
10/RFG/2-03 A/Prof Maria Kavallaris Advancing the treatment of lung cancer through the development of new therapeutic strategies. University of New South Wales $50,000
10/RFG/2-04 Prof Peter Karuso Development of fluorescent probes for early diagnosis of oesophageal and colorectal cancer. Macquarie University $49,566
10/RFG/2-12 Dr Megan Hitchins Development of novel methods for the discovery of interactions between gene promoter mutations and the epigenetic machinery. University of New South Wales $47,222
10/RFG/2-27 Prof Ian Cook Predicting dysphagia-related complications and improving outcomes in patients treated with head and neck radiotherapy South Eastern Sydney and Illawarra Area Health Service $48,393
10/RFG/2-32 Dr Daniel Catchpoole Implementing personalized medicine using global genomic similarity. University of Technology, Sydney $50,000
10/RFG/2-35 Prof Phyllis Butow Assessing unmet needs in women with gynaecological cancers; The first step University of Sydney $48,679
10/RFG/2-38 Dr Billie Bonevski Development of a web-based CME program on 'Sun and Vitamin D' for general practitioners. University of Newcastle $49,947
10/RFG/2-50 Prof Des Richardson The Effect of Anthracyclines on the Iron Metabolism of Leukaemia Cells. University of Sydney $49,922
10/RFG/2-55 Dr Tri Phan Development of novel in vivo fluorescent cell labelling tools and techniques for the molecular diagnosis of colorectal and esophageal cancer by laser scanning confocal endomicroscopy Garvan Institute of Medical Research $50,000
10/RFG/2-66 A/Prof Christopher Milross Development of a questionnaire to measure patients' & doctors' perceptions of the inconvenience associated with radiotherapy Sydney South West Area Health Service $49,913
10/RFG/2-80 Dr Daohai Zhang Examination of the tumour suppressor function of endoplasmic reticulum protein 29 (ERp29) in lung cancer and its therapeutic application University of Sydney $50,000
10/RFG/2-81 Dr Jason Wong Identifying transcriptional regulatory protein complexes in leukaemia University of New South Wales $50,000
10/RFG/2-85 Professor Nico van Zandwijk Identifying new plasma markers in mesothelioma Asbestos Diseases Research Institute $50,000
10/RFG/2-97 Dr Joanne Shaw Development of communication skills training for nurses delivering telephone-based supportive care interventions for people with cancer or their families University of Sydney $48,431
  $692,073

 

Translational Health Services Research Grants

Two to three year grants to further develop health service research capacity in NSW cancer services through collaborative partnerships between NSW academic institutions and clinical cancer services focussing on improved and innovative models of cancer service delivery (max $200,000 p.a.).

IDRecipientProject TitleAdministering InstitutionFunded
10/THS/2-01

Prof Andrew Biankin

Screening for Pancreatic Cancer in High Risk Australians

Garvan Institute of Medical Research

$599,771
10/THS/2-08

Prof Afaf Girgis

Feasibility study of an integrated, patient-centred psychosocial care model for patients with urological and head and neck cancers

University of Newcastle

$580,955
10/THS/2-14

Laureate Professor Rob Sanson-Fisher

Improving psychosocial outcomes for haematological cancer patients: An RCT

University of Newcastle

$583,475
  $1,764,201

 

Translational Program Grants

The Cancer Institute NSW Translational Program Grants are focussed on supporting multi-disciplinary approaches to cancer research that will rapidly translate research discoveries into clinical programs or policy.

IDRecipientProject TitleAdministering InstitutionFunded
10/TPG/1-01

Levon Khachigan

Novel Molecular Therapeutic Strategies Targeting c-June for Cutaneous Melanoma

University of New South Wales

$3,750,000

10/TPG/1-02

Graham Mann

Melanoma Institute Australia Translational Research program

University of Sydney

$3,736,512

10/TPG/1-03

Glenn Marshall

Targeting the Myc oncogenic signalling pathway for therapeutic intervention.

University of New South Wales

$3,739,491

10/TPG/1-04

Rob Sutherland

Personalised medicine for cancer: molecular biomarkers in clinical decision making for breast, prostate and pancreatic cancer.

Garvan Institute of Medical Research

$3,741,900

  $14,967,903

2009

Research Innovation Grants

These grants are one-off research grants to establish research data, proof-of-principal or important research concepts. They are aimed at making New South Wales cancer researchers more competitive for future funding by providing preliminary data to justify a larger grant. These grants are open to all disciplines of research to promote innovation and expertise in New South Wales cancer research.

IDRecipientProject TitleAdministering InstitutionFunded
09/RFG/2-13 Dr Kellie Charles A proteomic approach to identify predictive biomarkers of molecular targeted drugs. University of Sydney $50,000
09/RFG/2-15 Dr Daniel Christ Metabolic complications in childhood leukaemia survivors. Garvan Institute of Medical Research $49,909
09/RFG/2-21 Dr Richard Cohn Tamoxifen Dose Escalation in Patients with CYP2D6 Polymorphisms. Sydney West Area Health Service $46,600
09/RFG/2-27 A/Prof Howard Gurney Investigation of biomarkers for the diagnosis and prognosis of common cancers in the community such as breast, colorectal, prostate and head and neck cancers. Sydney West Area Health Service $50,000
09/RFG/2-29 Dr Beric Henderson The effect of colon cancer mutations on APC dynamics and function at the centrosome. University of Sydney $49,664
09/RFG/2-32 Prof David James Role of Acetyl CoA Carboxylase and lipid synthesis in Cancer. Garvan Institute of Medical Research $50,000
09/RFG/2-37 A/Prof Sharon Kilbreath Physiological prognostic indicators for lymphoedema in women treated for breast cancer. University of Sydney $48,250
09/RFG/2-38 Prof Madeleine King PROMIS: a new paradigm for quality of life assessment - a NSW-based proof-of-concept study University of Sydney $50,000
09/RFG/2-50 A/Prof Mark Molloy Multiplexed quantitation of phosphoproteins in tumours as prognostic markers. Macquarie University $50,000
09/RFG/2-58 Dr Phoebe Phillips Do Stromal Pancreatic Stellate Cells Contribute to Chemoresistance of Pancreatic Cancer Cells via Alteration of Multidrug Resistant Proteins? University of New South Wales $50,000
09/RFG/2-59 Dr John Pimanda Epigenetic Changes Associated with Pharmacotherapy in Myelodysplasia. University of New South Wales $50,000
09/RFG/2-64 Prof Bruce Robinson miRNA expression signatures and their functional significance in Medullary Thyroid Carcinoma. University of Sydney $50,000
09/RFG/2-65 Prof Phillip Robinson Proof-of principle kinomics approach to cancer research. Children's Medical Research Institute $50,000
09/RFG/2-69 A/Prof Caroline Smith Randomised controlled trial of acupuncture to reduce fatigue post breast cancer treatment: a pilot study. University of Western Sydney $49,697
09/RFG/2-81 A/Prof Jane Young Improving psychosocial outcomes for cancer carers: pilot study of a novel telephone intervention. University of Sydney $49,381
09/RFG/2-82 A/Prof Xu Dong Zhang Targeting Pro-Survival Mechanisms to Sensitize Human Melanoma to Immunotherapy. University of Newcastle $48,200
  $791,701

 

Translational Health Service Research Grants

Two to three year grants to further develop health service research capacity in NSW cancer services through collaborative partnerships between NSW academic institutions and clinical cancer services focussing on improved and innovative models of cancer service delivery.

IDRecipientProject TitleAdministering InstitutionFunded
09/THS/2-05 Prof Afaf Girgis;
Dr Colum Smith
Feasibility study of an oncology nurse practitioner model of care in a rural cancer setting. University of Newcastle $557,634
09/THS/2-10 Dr Sallie Anne Pearson;
Prof Robyn Ward
Measuring the use and impact of the Cancer Institute Standard Cancer Treatments Program in NSW hospitals. University of New South Wales $600,000
09/THS/2-12 A/Prof Jane Young;
Prof Michael Solomon
Improving colorectal cancer care coordination: centralised, tumour-specific or local, generic models of service delivery? University of Sydney $585,508
  $1,743,142

2008

Research Innovation Grants

These grants are one-off research grants to establish research data, proof-of-principal or important research concepts. They are aimed at making New South Wales cancer researchers more competitive for future funding by providing preliminary data to justify a larger grant. These grants are open to all disciplines of research to promote innovation and expertise in New South Wales cancer research.

IDRecipientProject TitleAdministering InstitutionFunded
08/RFG/1-11 Dr David Reilly Imaging cancer using hyperpolarized nanodiamond. University of Sydney $50,000
08/RFG/1-12 Dr Rachel Codd Biocombinatorial Synthesis of Histone Deacetylase Inhibitors as Chemotherapeutic Agents for Leukaemia and Lymphoma. University of Sydney $50,000
08/RFG/1-16 Dr Danuta Sandra Kalinowski Molecular Examination of the Role of Iron in Oestrogen-Dependent and -Independent Growth of Breast Cancer Cells. University of Sydney $50,000
08/RFG/1-17 Dr Xu Dong Zhang The MicroRNA Signature of Endoplasmic Reticulum Stress in Melanoma. Calvary Mater Newcastle $50,000
08/RFG/1-19 Dr Helen Warren-Forward An innovative program for role extension to utilise screening mammographers in addition to radiologists to assess screening mammograms. University of Newcastle $50,000
08/RFG/1-20 Laureate Prof Rob Sanson-Fisher Testing the acceptability of a system-oriented intervention, involving touch screen computers, for reducing cancer risk status among general practice patients. University of Newcastle $49,970
08/RFG/1-27 Dr Nikolas Haass Intravital cell-cycle imaging as a novel approach to design combined targeting strategies of independent signalling pathways in melanoma. University of Sydney $49,284
08/RFG/1-29 Dr Pall Thordarson Self-assembled gels for local anti-cancer drug delivery. University of New South Wales $50,000
08/RFG/1-30 Prof Martin Tattersall Exploring the influence of age-related factors in treatment decisions in advanced cancer. Sydney South West Area Health Service $50,000
08/RFG/1-31 Dr Sallie Anne Pearson Measuring the use and impact of the Cancer Institute NSW Standard Treatments Program in NSW hospitals: Developing and validating indicators. University of New South Wales $50,000
08/RFG/1-39 Dr James Lyons Polyclonality in cancer. University of Sydney $48,500
08/RFG/1-40 Dr Jason Wong A method for selective enrichment and analysis of the chlorotyrosine proteome in lung cancer. University of New South Wales $49,965
08/RFG/1-43 Dr Daniel Catchpoole Applications of systems biology for personalized medicine of childhood leukaemia. University of Sydney $48,380
08/RFG/1-44 Dr Meera Agar Randomised control trial of oral risperidone versus oral haloperidol versus oral placebo with rescue midazolam for delirium in palliative care. University of New South Wales $50,000
08/RFG/1-47 Dr Madeleine King Development of cancer-specific multi-attribute health states from the QLQ-C30 for use in economic evaluation. University of Sydney $47,814
08/RFG/1-65 Dr Diona Damian Immune effects of topical photodynamic therapy in humans. University of Sydney $50,000
08/RFG/1-68 Dr Alison Butt A phosphoproteomic approach to define novel molecular determinants of anti-estrogen resistance in breast cancer. Garvan Institute of Medical Research $50,000
08/RFG/1-76 Dr Jane Beith Feasibility of use of acupuncture for treatment of arthralgia secondary to aromatase inhibitor therapy in women with early breast cancer. Sydney South West Area Health Service $46,126
  $890,039

 

2005-2007

Outcomes